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Figure 4: Changes in body weight in A) lean mice and B) obese mice and changes in food intake in C) lean mice and D) obese mice, across the three different experimental treatment groups

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K., Hall, W

The 6J substrain has a deficiency of the mitochondrial enzyme nicotinamide nucleotide transhydrogenase (NNT), which transfers electron from NADH to NADP + thereby supporting the antioxidant glutathione peroxidase in mitochondria